Juvenile-onset systemic lupus erythematosus (jSLE) – Pathophysiological concepts and treatment options

The systemic autoimmune/inflammatory condition systemic lupus erythematosus (SLE) manifests before the age of 16 years in 10–20% of all cases. Clinical courses are more severe, and organ complications are more common in patients with juvenile SLE. Varying gender distribution in different age groups...

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Veröffentlicht in:	Best practice & research. Clinical rheumatology 2017-08, Vol.31 (4), p.488-504
Hauptverfasser:	Hedrich, Christian M., Smith, Eve M.D., Beresford, Michael W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune Autoinflammation Early-onset SLE Individualised Inflammation Juvenile-onset systemic lupus erythematosus SLE Target-directed Tissue damage Treatment
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