Negative feedback loop of autophagy and endoplasmic reticulum stress in rapamycin protection against renal ischemia‐reperfusion injury during initial reperfusion phase

ABSTRACT Rapamycin, an immunosuppressant, is widely used in patients with kidney transplant. However, the therapeutic effects of rapamycin remain controversial. Additionally, previous studies have revealed deleterious effects of rapamycin predominantly when administered for ≥24 h. Few studies, howev...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The FASEB journal 2018-11, Vol.32 (11), p.6002-6018
Hauptverfasser:	Li, Xinyuan, Zhu, Gongmin, Gou, Xin, He, Weiyang, Yin, Hubin, Yang, Xiaoyu, Li, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	acute kidney injury kidney transplantation sirolimus
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!