Pol32 is required for Polζ-dependent translesion synthesis and prevents double-strand breaks at the replication fork

POL32 encodes a non-essential subunit of Polδ and plays a role in Polδ processivity and DNA repair. In order to understand how Pol32 is involved in these processes, we performed extensive genetic analysis and demonstrated that POL32 is required for Polζ-mediated translesion synthesis, but not for Po...

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Veröffentlicht in:Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis 2007-12, Vol.625 (1), p.164-176
Hauptverfasser: Hanna, Michelle, Ball, Lindsay G., Tong, Amy H., Boone, Charles, Xiao, Wei
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Sprache:eng
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