IL‐13 and IL‐1β promote lung fibroblast growth through coordinated up‐regulation of PDGF‐AA and PDGF‐Rα

ABSTRACT Peribronchiolar fibrosis is a prominent feature of airway remodeling in asthma and involves fibroblast growth and collagen deposition. Interleukin‐13 (IL‐13), a T‐helper 2 cytokine, is a key mediator of airway remodeling in asthma, yet the mechanism through which IL‐13 promotes fibroblast g...

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Veröffentlicht in:	The FASEB journal 2004-07, Vol.18 (10), p.1132-1134
Hauptverfasser:	Ingram, Jennifer L., Rice, Annette B., Geisenhoffer, Kristen, Madtes, David K., Bonner, James C.
Format:	Artikel
Sprache:	eng
Schlagworte:	cellular proliferation cytokine receptors cytokines lung stromal cells
Online-Zugang:	Volltext
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