Thyroid FNAC: Causes of false‐positive results
In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity noninvasive follicular thyroid neoplasm with papi...
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Veröffentlicht in: | Cytopathology (Oxford) 2018-10, Vol.29 (5), p.407-417 |
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description | In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity noninvasive follicular thyroid neoplasm with papillary‐like nuclear features is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described.
This paper review the main causes of false positives in thyroid FNA and give some tips in how to avoid these mistakes. |
doi_str_mv | 10.1111/cyt.12575 |
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This paper review the main causes of false positives in thyroid FNA and give some tips in how to avoid these mistakes.</description><subject>Biopsy, Fine-Needle</subject><subject>Diagnosis, Differential</subject><subject>False Positive Reactions</subject><subject>false‐positive</subject><subject>follicular‐pattern lesions</subject><subject>Humans</subject><subject>Inflammation</subject><subject>noninvasive follicular thyroid neoplasm with papillary‐like nuclear features</subject><subject>Sensitivity and Specificity</subject><subject>Thyroid</subject><subject>thyroid carcinoma</subject><subject>Thyroid Diseases - pathology</subject><subject>thyroid FNA</subject><subject>Thyroid gland</subject><subject>Thyroid Gland - pathology</subject><issn>0956-5507</issn><issn>1365-2303</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10LFOwzAQBmALgWgpDLwAisQCQ9rzuY4TtiqigFTBUgYmy0lskSptit2AsvEIPCNPgmkKAxK33HCffp1-Qk4pDKmfUd5uhhS54HukT1nEQ2TA9kkfEh6FnIPokSPnFgAUE2SHpIeJiOJIiD6B-XNr67IIpveT9CpIVeO0C2oTGFU5_fn-sa5duSlfdWC1a6qNOyYH29PJbg_I4_R6nt6Gs4ebu3QyC3MWxzwcQ8ZihUnEAAuWIVMsR0oNz5ThNEPU2sSFUoprHhXcoMlplLNMKa_HwrABuehy17Z-abTbyGXpcl1VaqXrxkmEMQgBwLin53_oom7syn8nkQLGCSQUvLrsVG5r56w2cm3LpbKtpCC_a5S-Rrmt0duzXWKTLXXxK39682DUgbey0u3_STJ9mneRX8U1e1E</recordid><startdate>201810</startdate><enddate>201810</enddate><creator>Malheiros, D. C.</creator><creator>Canberk, S.</creator><creator>Poller, D. N.</creator><creator>Schmitt, F.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-1006-6946</orcidid></search><sort><creationdate>201810</creationdate><title>Thyroid FNAC: Causes of false‐positive results</title><author>Malheiros, D. C. ; Canberk, S. ; Poller, D. N. ; Schmitt, F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3885-40b38a296302d3b23a3c211f5baf51b22eef8daaa5e56d5f2fc16c3baad3b47f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Biopsy, Fine-Needle</topic><topic>Diagnosis, Differential</topic><topic>False Positive Reactions</topic><topic>false‐positive</topic><topic>follicular‐pattern lesions</topic><topic>Humans</topic><topic>Inflammation</topic><topic>noninvasive follicular thyroid neoplasm with papillary‐like nuclear features</topic><topic>Sensitivity and Specificity</topic><topic>Thyroid</topic><topic>thyroid carcinoma</topic><topic>Thyroid Diseases - pathology</topic><topic>thyroid FNA</topic><topic>Thyroid gland</topic><topic>Thyroid Gland - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Malheiros, D. C.</creatorcontrib><creatorcontrib>Canberk, S.</creatorcontrib><creatorcontrib>Poller, D. N.</creatorcontrib><creatorcontrib>Schmitt, F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Cytopathology (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Malheiros, D. C.</au><au>Canberk, S.</au><au>Poller, D. N.</au><au>Schmitt, F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thyroid FNAC: Causes of false‐positive results</atitle><jtitle>Cytopathology (Oxford)</jtitle><addtitle>Cytopathology</addtitle><date>2018-10</date><risdate>2018</risdate><volume>29</volume><issue>5</issue><spage>407</spage><epage>417</epage><pages>407-417</pages><issn>0956-5507</issn><eissn>1365-2303</eissn><abstract>In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity noninvasive follicular thyroid neoplasm with papillary‐like nuclear features is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described.
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subjects | Biopsy, Fine-Needle Diagnosis, Differential False Positive Reactions false‐positive follicular‐pattern lesions Humans Inflammation noninvasive follicular thyroid neoplasm with papillary‐like nuclear features Sensitivity and Specificity Thyroid thyroid carcinoma Thyroid Diseases - pathology thyroid FNA Thyroid gland Thyroid Gland - pathology |
title | Thyroid FNAC: Causes of false‐positive results |
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