Thyroid FNAC: Causes of false‐positive results

In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity noninvasive follicular thyroid neoplasm with papi...

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Veröffentlicht in:Cytopathology (Oxford) 2018-10, Vol.29 (5), p.407-417
Hauptverfasser: Malheiros, D. C., Canberk, S., Poller, D. N., Schmitt, F.
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creator Malheiros, D. C.
Canberk, S.
Poller, D. N.
Schmitt, F.
description In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity noninvasive follicular thyroid neoplasm with papillary‐like nuclear features is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described. This paper review the main causes of false positives in thyroid FNA and give some tips in how to avoid these mistakes.
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subjects Biopsy, Fine-Needle
Diagnosis, Differential
False Positive Reactions
false‐positive
follicular‐pattern lesions
Humans
Inflammation
noninvasive follicular thyroid neoplasm with papillary‐like nuclear features
Sensitivity and Specificity
Thyroid
thyroid carcinoma
Thyroid Diseases - pathology
thyroid FNA
Thyroid gland
Thyroid Gland - pathology
title Thyroid FNAC: Causes of false‐positive results
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