Using poly(l-lactic acid) and poly(ɛ-caprolactone) blends to fabricate self-expanding, watertight and biodegradable surgical patches for potential fetoscopic myelomeningocele repair

Our study focuses on the development and characterization of a self-expanding, watertight and biodegradable patch for fetoscopic myelomeningocele (MMC) prenatal repair. We fabricated poly(l-lactic acid) (PLA) and poly(ɛ-caprolactone) (PCL) blend films by solution casting. Formulation c with average...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2019-02, Vol.107 (2), p.295-305
Hauptverfasser:	Tatu, Rigwed, Oria, Marc, Pulliam, Sarah, Signey, Lorenzo, Rao, Marepalli B, Peiro, Jose L, Lin, Chia-Ying
Format:	Artikel
Sprache:	eng
Schlagworte:	Amniotic fluid Biocompatibility Biodegradability Biodegradation Biomedical materials Carbonyls Cytotoxicity Degradation Fibroblasts Functional groups Glass transition temperature Lactic acid Materials research Materials science Patches (structures) Permeability Polymers Surgery Toxicity Transition temperatures Weight loss
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