Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

Natural killer cells (NKs) are abundant in the human decidua, regulating trophoblast invasion and angiogenesis. Several diseases of poor placental development are associated with first pregnancies, so we thus looked to characterize differences in decidual NKs (dNKs) in first versus repeated pregnanc...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2018-05, Vol.48 (5), p.951-962.e5
Hauptverfasser:	Gamliel, Moriya, Goldman-Wohl, Debra, Isaacson, Batya, Gur, Chamutal, Stein, Natan, Yamin, Rachel, Berger, Michael, Grunewald, Myriam, Keshet, Eli, Rais, Yoach, Bornstein, Chamutal, David, Eyal, Jelinski, Adam, Eisenberg, Iris, Greenfield, Caryn, Ben-David, Arbel, Imbar, Tal, Gilad, Ronit, Haimov-Kochman, Ronit, Mankuta, David, Elami-Suzin, Matan, Amit, Ido, Hanna, Jacob H., Yagel, Simcha, Mandelboim, Ofer
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Chromatin Councils Cytokines Cytomegalovirus Decidua Endometrium Epigenetics Gene expression gravidity great obstetrical disorders LILRB1 Natural killer cells NKG2 antigen NKG2C Placenta Population Preeclampsia Pregnancy Receptors Secretion Stem cells trained immunity Uterus Womens health γ-Interferon
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