Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease

Parkinson's disease (PD) progression is heterogeneous. Variants in PD-related genes may alter disease progression or severity. We examined if the single nucleotide variant rs6265 in the gene Bdnf alters clinical phenotype in early-stage, unmedicated PD. A retrospective analysis was conducted us...

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Veröffentlicht in:	Parkinsonism & related disorders 2018-08, Vol.53, p.70-75
Hauptverfasser:	Fischer, D. Luke, Auinger, Peggy, Goudreau, John L., Paumier, Katrina L., Cole-Strauss, Allyson, Kemp, Christopher J., Lipton, Jack W., Sortwell, Caryl E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain-derived neurotrophic factor Levodopa rs6265 Single nucleotide polymorphism Val66Met
Online-Zugang:	Volltext
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