Mathematical model of hypertension-induced arterial remodeling: A chemo-mechanical approach

•A mathematical model of arterial remodeling during the onset of hypertension.•Includes the interaction of primary mechanical, biological, and biochemical determinants of hypertension.•Models onset and impact of endothelial dysfunction.•Simulations align with published results for hypertensive rats....

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Veröffentlicht in:	Mathematical biosciences 2018-09, Vol.303, p.10-25
Hauptverfasser:	Wilstein, Zahava, Alligood, Daniel M., McLure, Valerie L., Miller, Austinn C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arterial remodeling Biological activity Collagen Differential equations Elasticity Endothelial dysfunction Hypertension Integral equations Mathematical model Mathematical models Nitric oxide Organic chemistry Rat carotid Reactive oxygen species Vasodilation
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