Inhibitory Effects of Moutan Cortex on Immediate Allergic Reactions

The anti-allergic effect of an ethanol extract from Moutan Cortex was evaluated in some animal models. The Moutan Cortex extract (30, 100 mg/kg, i.p.) dose-dependently inhibited systemic anaphylactic shock induced by compound 48/80 in mice. It also inhibited dose-dependently the scratching behavior...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2007/09/01, Vol.30(9), pp.1707-1710
Hauptverfasser:	Jiang, Shuishi, Nakano, Yoshiyuki, Yatsuzuka, Rie, Ono, Rie, Kamei, Chiaki
Format:	Artikel
Sprache:	eng
Schlagworte:	anaphylactic shock Anaphylaxis - chemically induced Anaphylaxis - drug therapy Animals Anti-Allergic Agents Capillary Permeability - drug effects compound 48/80 Ethanol Female Histamine - pharmacology Histamine Release - drug effects Hypersensitivity, Immediate - drug therapy Hypersensitivity, Immediate - psychology Indicators and Reagents mast cell Mast Cells - drug effects Mast Cells - metabolism Mice Mice, Inbred ICR Moutan Cortex p-Methoxy-N-methylphenethylamine - pharmacology Paeonia - chemistry Plant Bark - chemistry Plant Extracts - pharmacology Plant Roots - chemistry scratching behavior Solvents vascular permeability
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