Effect of stent implantation on blood pressure control in adults with coarctation of the aorta
Stenting of coarctation of the aorta (CoA) generally results in good angiographic results and a decrease in transcoarctation pressure gradient. However, effect on blood pressure control is less clear. The goal of the current retrospective analysis was to investigate the effects of CoA stenting on bl...
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| Veröffentlicht in: | Cardiovascular revascularization medicine 2018-12, Vol.19 (8), p.944-950 |
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| creator | van der Burg, Jennifer J. Warmerdam, Evangeline G. Krings, Gregor J. Meijboom, Folkert J. van Dijk, Arie P. Post, Marco C. Veen, Gerrit Voskuil, Michiel Sieswerda, Gertjan Tj |
| description | Stenting of coarctation of the aorta (CoA) generally results in good angiographic results and a decrease in transcoarctation pressure gradient. However, effect on blood pressure control is less clear. The goal of the current retrospective analysis was to investigate the effects of CoA stenting on blood pressure control.
A retrospective analysis was conducted in consecutive adult patients with a CoA who underwent a percutaneous intervention at one of the three participating hospitals. Measurements included office blood pressure, invasive peak-to-peak systolic pressure over the CoA, diameter of the intima lumen at the narrowest part of the CoA and use of medication. The follow-up data were obtained, based on the most recent examination date.
There were 26 native CoA and 17 recurrent CoAs (total n = 43). Seven of them underwent two procedures. Mean peak-to-peak gradient decreased from 27 mmHg to 3 mmHg (p |
| doi_str_mv | 10.1016/j.carrev.2018.03.018 |
| format | Article |
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A retrospective analysis was conducted in consecutive adult patients with a CoA who underwent a percutaneous intervention at one of the three participating hospitals. Measurements included office blood pressure, invasive peak-to-peak systolic pressure over the CoA, diameter of the intima lumen at the narrowest part of the CoA and use of medication. The follow-up data were obtained, based on the most recent examination date.
There were 26 native CoA and 17 recurrent CoAs (total n = 43). Seven of them underwent two procedures. Mean peak-to-peak gradient decreased from 27 mmHg to 3 mmHg (p < 0.001), and minimal diameter increased from a mean of 11 mm to 18 mm (p < 0.001). Mean systolic blood pressure decreased from 151 ± 18 mmHg to 135 ± 19 mmHg at first follow-up of 3.8 ± 1.9 months and 137 ± 22 mmHg at latest follow-up of 19.5 ± 10.9 months (p = 0.001 and p = 0.009, compared to baseline, respectively). The total number of hypertensive patients decreased from 74% to 27% at latest follow-up. No significant change in antihypertensive medication was observed.
A clinically significant decrease in systolic blood pressure of approximately 16 mmHg was shown after (re)intervention in CoA patients, which sustained at follow-up. This sustained decrease of blood pressure can be expected to lead to less future adverse cardiovascular events.</description><identifier>ISSN: 1553-8389</identifier><identifier>EISSN: 1878-0938</identifier><identifier>DOI: 10.1016/j.carrev.2018.03.018</identifier><identifier>PMID: 29752138</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Coarctation of the aorta ; Hypertension ; Percutaneous intervention</subject><ispartof>Cardiovascular revascularization medicine, 2018-12, Vol.19 (8), p.944-950</ispartof><rights>2018 Elsevier Inc.</rights><rights>Copyright © 2018 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-3b530456c134722a774a1a03e729b0d2d41eb7f74292364b8c789b2528b908e13</citedby><cites>FETCH-LOGICAL-c362t-3b530456c134722a774a1a03e729b0d2d41eb7f74292364b8c789b2528b908e13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.carrev.2018.03.018$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29752138$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>van der Burg, Jennifer J.</creatorcontrib><creatorcontrib>Warmerdam, Evangeline G.</creatorcontrib><creatorcontrib>Krings, Gregor J.</creatorcontrib><creatorcontrib>Meijboom, Folkert J.</creatorcontrib><creatorcontrib>van Dijk, Arie P.</creatorcontrib><creatorcontrib>Post, Marco C.</creatorcontrib><creatorcontrib>Veen, Gerrit</creatorcontrib><creatorcontrib>Voskuil, Michiel</creatorcontrib><creatorcontrib>Sieswerda, Gertjan Tj</creatorcontrib><title>Effect of stent implantation on blood pressure control in adults with coarctation of the aorta</title><title>Cardiovascular revascularization medicine</title><addtitle>Cardiovasc Revasc Med</addtitle><description>Stenting of coarctation of the aorta (CoA) generally results in good angiographic results and a decrease in transcoarctation pressure gradient. However, effect on blood pressure control is less clear. The goal of the current retrospective analysis was to investigate the effects of CoA stenting on blood pressure control.
A retrospective analysis was conducted in consecutive adult patients with a CoA who underwent a percutaneous intervention at one of the three participating hospitals. Measurements included office blood pressure, invasive peak-to-peak systolic pressure over the CoA, diameter of the intima lumen at the narrowest part of the CoA and use of medication. The follow-up data were obtained, based on the most recent examination date.
There were 26 native CoA and 17 recurrent CoAs (total n = 43). Seven of them underwent two procedures. Mean peak-to-peak gradient decreased from 27 mmHg to 3 mmHg (p < 0.001), and minimal diameter increased from a mean of 11 mm to 18 mm (p < 0.001). Mean systolic blood pressure decreased from 151 ± 18 mmHg to 135 ± 19 mmHg at first follow-up of 3.8 ± 1.9 months and 137 ± 22 mmHg at latest follow-up of 19.5 ± 10.9 months (p = 0.001 and p = 0.009, compared to baseline, respectively). The total number of hypertensive patients decreased from 74% to 27% at latest follow-up. No significant change in antihypertensive medication was observed.
A clinically significant decrease in systolic blood pressure of approximately 16 mmHg was shown after (re)intervention in CoA patients, which sustained at follow-up. This sustained decrease of blood pressure can be expected to lead to less future adverse cardiovascular events.</description><subject>Coarctation of the aorta</subject><subject>Hypertension</subject><subject>Percutaneous intervention</subject><issn>1553-8389</issn><issn>1878-0938</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LAzEQhoMotlb_gUiOXnbNx-4mexGk1A8oeNGrIZudpSnbTU2yFf-9Ka0eHQbeEN53hnkQuqYkp4RWd-vcaO9hlzNCZU54nuQETakUMiM1l6fpXZY8k1zWE3QRwpoQLlglztGE1aJklMsp-lh0HZiIXYdDhCFiu9n2eog6Wjfg1E3vXIu3HkIYPWDjhuhdj-2AdTv2MeAvG1fpW3vzG-pwXAHWzkd9ic463Qe4OuoMvT8u3ubP2fL16WX-sMwMr1jMeFNyUpSVobwQjGkhCk014SBY3ZCWtQWFRnSiYDXjVdFII2TdsJLJpiYSKJ-h28PcrXefI4SoNjYY6NMp4MagGOGSiX0la3GwGu9C8NCprbcb7b8VJWpPVq3Vgazak1WEqyQpdnPcMDYbaP9CvyiT4f5ggHTnzoJXwVgYDLTWJ8Kqdfb_DT9sqYua</recordid><startdate>201812</startdate><enddate>201812</enddate><creator>van der Burg, Jennifer J.</creator><creator>Warmerdam, Evangeline G.</creator><creator>Krings, Gregor J.</creator><creator>Meijboom, Folkert J.</creator><creator>van Dijk, Arie P.</creator><creator>Post, Marco C.</creator><creator>Veen, Gerrit</creator><creator>Voskuil, Michiel</creator><creator>Sieswerda, Gertjan Tj</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201812</creationdate><title>Effect of stent implantation on blood pressure control in adults with coarctation of the aorta</title><author>van der Burg, Jennifer J. ; Warmerdam, Evangeline G. ; Krings, Gregor J. ; Meijboom, Folkert J. ; van Dijk, Arie P. ; Post, Marco C. ; Veen, Gerrit ; Voskuil, Michiel ; Sieswerda, Gertjan Tj</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-3b530456c134722a774a1a03e729b0d2d41eb7f74292364b8c789b2528b908e13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Coarctation of the aorta</topic><topic>Hypertension</topic><topic>Percutaneous intervention</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van der Burg, Jennifer J.</creatorcontrib><creatorcontrib>Warmerdam, Evangeline G.</creatorcontrib><creatorcontrib>Krings, Gregor J.</creatorcontrib><creatorcontrib>Meijboom, Folkert J.</creatorcontrib><creatorcontrib>van Dijk, Arie P.</creatorcontrib><creatorcontrib>Post, Marco C.</creatorcontrib><creatorcontrib>Veen, Gerrit</creatorcontrib><creatorcontrib>Voskuil, Michiel</creatorcontrib><creatorcontrib>Sieswerda, Gertjan Tj</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cardiovascular revascularization medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van der Burg, Jennifer J.</au><au>Warmerdam, Evangeline G.</au><au>Krings, Gregor J.</au><au>Meijboom, Folkert J.</au><au>van Dijk, Arie P.</au><au>Post, Marco C.</au><au>Veen, Gerrit</au><au>Voskuil, Michiel</au><au>Sieswerda, Gertjan Tj</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of stent implantation on blood pressure control in adults with coarctation of the aorta</atitle><jtitle>Cardiovascular revascularization medicine</jtitle><addtitle>Cardiovasc Revasc Med</addtitle><date>2018-12</date><risdate>2018</risdate><volume>19</volume><issue>8</issue><spage>944</spage><epage>950</epage><pages>944-950</pages><issn>1553-8389</issn><eissn>1878-0938</eissn><abstract>Stenting of coarctation of the aorta (CoA) generally results in good angiographic results and a decrease in transcoarctation pressure gradient. However, effect on blood pressure control is less clear. The goal of the current retrospective analysis was to investigate the effects of CoA stenting on blood pressure control.
A retrospective analysis was conducted in consecutive adult patients with a CoA who underwent a percutaneous intervention at one of the three participating hospitals. Measurements included office blood pressure, invasive peak-to-peak systolic pressure over the CoA, diameter of the intima lumen at the narrowest part of the CoA and use of medication. The follow-up data were obtained, based on the most recent examination date.
There were 26 native CoA and 17 recurrent CoAs (total n = 43). Seven of them underwent two procedures. Mean peak-to-peak gradient decreased from 27 mmHg to 3 mmHg (p < 0.001), and minimal diameter increased from a mean of 11 mm to 18 mm (p < 0.001). Mean systolic blood pressure decreased from 151 ± 18 mmHg to 135 ± 19 mmHg at first follow-up of 3.8 ± 1.9 months and 137 ± 22 mmHg at latest follow-up of 19.5 ± 10.9 months (p = 0.001 and p = 0.009, compared to baseline, respectively). The total number of hypertensive patients decreased from 74% to 27% at latest follow-up. No significant change in antihypertensive medication was observed.
A clinically significant decrease in systolic blood pressure of approximately 16 mmHg was shown after (re)intervention in CoA patients, which sustained at follow-up. This sustained decrease of blood pressure can be expected to lead to less future adverse cardiovascular events.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>29752138</pmid><doi>10.1016/j.carrev.2018.03.018</doi><tpages>7</tpages></addata></record> |
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| subjects | Coarctation of the aorta Hypertension Percutaneous intervention |
| title | Effect of stent implantation on blood pressure control in adults with coarctation of the aorta |
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