Structural Delineation of the Neck Linker of Kinesin-3 for Processive Movement

Processive kinesin motors contain a neck linker (NL) that mediates the chemo-mechanical coupling and controls the directionality and processivity. However, kinesin-3 NL remains poorly determined due to the lack of the structural information of the junction with the following neck coil (NC). Here, we...

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Veröffentlicht in:	Journal of molecular biology 2018-07, Vol.430 (14), p.2030-2041
Hauptverfasser:	Ren, Jinqi, Zhang, Yong, Wang, Shuang, Huo, Lin, Lou, Jizhong, Feng, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	interaction intracellular transport molecular dynamics simulation molecular motor X-ray crystallography
Online-Zugang:	Volltext
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