Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish

The genetic underpinnings that orchestrate the vertebrate heart rate are not fully understood yet, but of high clinical importance, since diseases of cardiac impulse formation and propagation are common and severe human arrhythmias. To identify novel regulators of the vertebrate heart rate, we decip...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 2018-07, Vol.120, p.42-52
Hauptverfasser:	Pott, Alexander, Bock, Sarah, Berger, Ina M., Frese, Karen, Dahme, Tillman, Keßler, Mirjam, Rinné, Susanne, Decher, Niels, Just, Steffen, Rottbauer, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	Bradycardia Forward genetics Long-QT Na+/K+-ATPase Refractoriness Zebrafish
Online-Zugang:	Volltext
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