ClC-3 chloride channel protein induces G1 arrest in hepatocellular carcinoma Hep3B cells

ClC-3 is a type of chloride channel that has multiple functions in tumorigenesis and tumor growth, and can be blocked by DIDS (4,4'-diisothiocyanostilbene-2,2'-disulfonic acid). In the present study, we found that DIDS inhibited the proliferation of Hep3B hepatocellular carcinoma (HCC) cel...

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Veröffentlicht in:	Oncology reports 2018-07, Vol.40 (1), p.472-478
Hauptverfasser:	Wang, Rui, Kang, Bijun, Hu, Rendong, Huang, Youwai, Qin, Zixi, Du, Jichen, Lin, Xi
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer therapies Care and treatment Cell cycle Cell growth Chemotherapy Chloride Development and progression Gene expression Genetic aspects Health aspects Hepatocellular carcinoma Hypotheses Innovations Ion channels Kinases Laboratories Liver cancer Lung cancer Medical prognosis Membranes Molecular targeted therapy Patients Proteins Studies
Online-Zugang:	Volltext
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