R-spondin3 Is Associated with Basal-Progenitor Behavior in Normal and Tumor Mammary Cells

R-spondin3 (RSPO3) is a member of a family of secreted proteins that enhance Wnt signaling pathways in diverse processes, including cancer. However, the role of RSPO3 in mammary gland and breast cancer development remains unclear. In this study, we show that RSPO3 is expressed in the basal stem cell...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2018-08, Vol.78 (16), p.4497-4511
Hauptverfasser: Tocci, Johanna M, Felcher, Carla M, García Solá, Martín E, Goddio, María Victoria, Zimberlin, María Noel, Rubinstein, Natalia, Srebrow, Anabella, Coso, Omar A, Abba, Martín C, Meiss, Roberto P, Kordon, Edith C
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Sprache:eng
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