Increased hyperalgesia by 5-nitro-2, 3-(phenylpropylamino)-benzoic acid (NPPB), a chloride channel blocker in crush injury-induced neuropathic pain in rats

Chloride channels belong to diverse group of anion selective channels involved in different signaling processes. The present study was planned to investigate the involvement of chloride channels in crush injury-induced neuropathic pain in rats by using ivermectin, a ligand gated chloride channel ope...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2009, Vol.91 (3), p.417-422
Hauptverfasser:	Ramteke, Vinod D., Tandan, Surendra K., Kumar, Dinesh, Aruna Devi, R., Shukla, Manoj K., Ravi Prakash, Vellanki
Format:	Artikel
Sprache:	eng
Schlagworte:	5-nitro-2, 3-(phenylpropylamino)-benzoic acid (NPPB) Angiogenesis Inhibitors Animals Behavior, Animal - drug effects Biological and medical sciences Chloride channel Chloride Channels - antagonists & inhibitors Cold Temperature Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction Hot Temperature Hyperalgesia - chemically induced Hyperalgesia - pathology Hyperalgesia - psychology Injections, Intraventricular Ivermectin Ivermectin - pharmacology Ligands Male Medical sciences Nerve Crush Nervous system (semeiology, syndromes) Neurology Neuropathic pain Nitrobenzoates Pain - pathology Pain - psychology Pain Threshold - drug effects Peripheral Nervous System Diseases - pathology Peripheral Nervous System Diseases - psychology Physical Stimulation Rats Rats, Wistar
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