The FGF14 super(F145S) Mutation Disrupts the Interaction of FGF14 with Voltage-Gated Na super(+) Channels and Impairs Neuronal Excitability

Fibroblast growth factor 14 (FGF14) belongs to the intracellular FGF homologous factor subfamily of FGF proteins (iFGFs) that are not secreted and do not activate tyrosine kinase receptors. The iFGFs, however, have been shown to interact with the pore-forming ( alpha ) subunits of voltage-gated Na s...

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Veröffentlicht in:	The Journal of neuroscience 2007-10, Vol.27 (44), p.12033-12044
Hauptverfasser:	Laezza, Fernanda, Gerber, Benjamin R, Lou, Jun-Yang, Kozel, Marie A, Hartman, Hali, Marie Craig, Ann, Ornitz, David M, Nerbonne, Jeanne M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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