Evaluation of the rivastigmine role against botulinum toxin-A-induced osteoporosis in albino rats: A biochemical, histological, and immunohistochemical study

The present study aimed to evaluate the role of rivastigmine against the effect of a single unilateral botulinum toxin-A (BTX-A) injection on the bone and bone marrow of adult albino rats 4 weeks after injection. Twenty-four Wistar albino rats were divided into four equal groups: group I, which rece...

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Veröffentlicht in:	Human & experimental toxicology 2018-12, Vol.37 (12), p.1323-1335
Hauptverfasser:	Ali, DM, Abdelzaher, WY, Abdel-Hafez, SMN
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Albinism Alkaline phosphatase Animals Antigens, CD - metabolism Antigens, Differentiation, Myelomonocytic - metabolism Biocompatibility Biomedical materials Bone marrow Botulinum toxin Botulinum Toxins, Type A C-reactive protein Calcium Calcium - blood Cancellous bone Cholinesterase Inhibitors - pharmacology Cholinesterase Inhibitors - therapeutic use Distilled water Femur Femur - drug effects Femur - metabolism Femur - pathology Glutathione Glutathione - metabolism Immunohistochemistry Injection Macrophages Malondialdehyde Malondialdehyde - metabolism Osteoclastogenesis Osteoclasts Osteoporosis Osteoporosis - chemically induced Osteoporosis - drug therapy Osteoporosis - metabolism Osteoporosis - pathology Phosphorus Proteins Rats Rats, Wistar Rivastigmine Rivastigmine - pharmacology Rivastigmine - therapeutic use Toxicity Tumor necrosis factor-α
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