Allergen immunotherapy: current and new therapeutic strategies

Allergic individuals respond to an environmental allergen encounter by producing T-cell cytokines, predominantly IL-4 and IL-5, which in turn drive the production of allergen-specific IgE antibodies and recruitment of an eosinophil-rich inflammatory infiltrate. Allergen-specific immunotherapy (SIT)...

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Veröffentlicht in:	Expert opinion on investigational drugs 2000-03, Vol.9 (3), p.515-527
Hauptverfasser:	Rolland, Jennifer M, Douglass, Jo, O'Hehir, Robyn E
Format:	Artikel
Sprache:	eng
Schlagworte:	allergen Allergens - immunology Allergens - therapeutic use Animals asthma cytokines Cytokines - immunology DNA vaccine Humans Hypersensitivity - immunology Hypersensitivity - therapy IgE antibody immunotherapy Immunotherapy - methods peptide rhinoconjunctivitis T-cell T-Lymphocytes - immunology vaccine
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