MC1R: three novel variants identified in a malignant melanoma association study in the Spanish population

The human melanocortin-1 receptor (MC1R) gene, which plays a crucial role in pigmentation, also appears to be important in malignant melanoma (MM). This case–control study in the Spanish population included 116 consecutive MM patients and 188 controls frequency matched for sex and age. Sequence anal...

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Veröffentlicht in:	Carcinogenesis (New York) 2007-08, Vol.28 (8), p.1659-1664
Hauptverfasser:	Fernandez, LP, Milne, RL, Bravo, J, Lopez, JM, Avilés, JA, Longo, MI, Benítez, J, Lázaro, P, Ribas, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution - genetics Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Case-Control Studies Dermatology Female Gene Frequency Genetic Predisposition to Disease Genetic Variation Genetics, Population Haplotypes Humans Male Medical sciences Melanoma - genetics Middle Aged Receptor, Melanocortin, Type 1 - genetics Risk Factors Spain Tumors Tumors of the skin and soft tissue. Premalignant lesions
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