Subjective Cognitive Decline Is Associated With Altered Default Mode Network Connectivity in Individuals With a Family History of Alzheimer’s Disease

Both subjective cognitive decline (SCD) and a family history of Alzheimer’s disease (AD) portend risk of brain abnormalities and progression to dementia. Posterior default mode network (pDMN) connectivity is altered early in the course of AD. It is unclear whether SCD predicts similar outcomes in co...

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Veröffentlicht in:	Biological psychiatry : cognitive neuroscience and neuroimaging 2018-05, Vol.3 (5), p.463-472
Hauptverfasser:	Verfaillie, Sander C.J., Vachon-Presseau, Etienne, Tabrizi, Shirin, Savard, Mélissa, Bellec, Pierre, Ossenkoppele, Rik, Scheltens, Philip, Breitner, John C.S., Villeneuve, Sylvia, Anthal, Elena, Appleby, Melissa, Ayranci, Gülebru, Barkun, Alan, Beaudry, Thomas, Benbouhoud, Fatiha, Bohbot, Veronique, Breitner, John, Carmo, Leopoldina, Carrier Charles, Edouard, Chakravarty, Mallar, Cheewakriengkrai, Laksanun, Collins, Louis, Courcot, Blandine, Craft, Suzanne, Cuello, Claudio, Dadar, Mahsa, DasSamir, Dea, Doris, Debacker, Clement, Dubuc, Sylvie, Duclair, Guerda, Dufour, Marianne, Eisenberg, Mark, El-Khoury, Rana, Etienne, Pierre, Evans, Alan, Faubert, Anne-Marie, Ferdinand, Fabiola, Fonov, Vladimir, Fontaine, David, Frappier, Josée, Joanne, Frenette, Gagne, Guylaine, Gauthier, Serge, Gervais, Valérie, Giles, Renuka, Gonneaud, Julie, Gordon, Renee, Ituria-Medina, Yasser, Jack, Clifford, Kat, Justin, Kazazian, Christina, Khachaturian, Zaven, Kostopoulos, Penelope, Labonte, Anne, Lafaille-Magnan, Marie-Elyse, Lee, Tanya, Leoutsakos, Jeannie-Marie, Lepage, Claude, Leppert, Illana, Madjar, Cécile, Mahar, Laura, Maltais, Jean-Robert, Mathotaarachchi, Sulantha, Meyer, Pierre-François, Montine, Thomas, Morris, John, Nair, Vasavan, Orban, Pierre, Page, Véronique, Pascoal, Tharick, Petkova, Mirela, Picard, Cynthia, Pichet Binette, Alexa, Pogossova, Galina, Poirier, Judes, Pruessner, Jens, Rajah, Natasha, Rioux, Pierre, Rosa-Neto, Pedro, Sager, Mark, Saint-Fort, Eunice Farah, Sperling, Reisa, Tam, Angela, Tardif, Christine, Tariot, Pierre, Teigner, Eduard, Theroux, Louise, Toussaint, Paule-Joanne, Tremblay-Mercier, Jennifer, Tuwaig, Miranda, Vallee, Isabelle, Verfaillie, Sander, Vogel, Jacob, Wan, Karen, Wang, Seqian, Yu, Elsa
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer Disease - psychology Alzheimer’s disease Brain Mapping Cognition Cognition - physiology Cognitive Dysfunction - psychology Default mode network connectivity Disease Progression Family history of dementia Female Humans Magnetic Resonance Imaging Male Middle Aged Neural Pathways - physiopathology Neuropsychological Tests Resting-state functional MRI Subjective cognitive decline
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