The role of xanthine oxidoreductase and uric acid in metabolic syndrome

Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome through the oxidative stress and the inflammatory response induced by XOR-derived reactive oxygen species and uric acid. Hyperuricemia is strongly linked to hypertension, insulin resistance, obesity and hypertri...

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Veröffentlicht in:	Biochimica et biophysica acta. Molecular basis of disease 2018-08, Vol.1864 (8), p.2557-2565
Hauptverfasser:	Battelli, Maria Giulia, Bortolotti, Massimo, Polito, Letizia, Bolognesi, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - metabolism Adipocytes - pathology Adipogenesis Animals Cardiovascular diseases Cell Differentiation Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Humans Hypertension - metabolism Hypertension - pathology Hyperuricemia - metabolism Hyperuricemia - pathology Metabolic syndrome Metabolic Syndrome - metabolism Metabolic Syndrome - pathology Oncogenesis Oxidative stress Uric acid Uric Acid - metabolism Xanthine Dehydrogenase - metabolism Xanthine oxidoreductase
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