Primary cutaneous cribriform apocrine carcinoma: Case report and literature review
Primary cutaneous cribriform apocrine carcinoma is a rare but distinct variant of primary cutaneous apocrine carcinoma and it is considered a low grade malignancy. We herein present a case of primary cutaneous cribriform apocrine carcinoma at the neck of a 26-year-old female. The tumor features a re...
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Veröffentlicht in: | Indian journal of dermatology, venereology, and leprology venereology, and leprology, 2018-09, Vol.84 (5), p.569-572 |
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description | Primary cutaneous cribriform apocrine carcinoma is a rare but distinct variant of primary cutaneous apocrine carcinoma and it is considered a low grade malignancy. We herein present a case of primary cutaneous cribriform apocrine carcinoma at the neck of a 26-year-old female. The tumor features a relatively well-circumscribed border and multiple aggregations of mildly pleomorphic epithelial cells with large ovoid nuclei, small nucleoli and abundant eosinophilic cytoplasms. Cribriform and tubular structures are the major architectural patterns. The primary differential diagnosis is cutaneous metastasis from a cribriform visceral carcinoma; others include primary secretory carcinoma of the skin, adenoid cystic basal cell carcinoma and primary cutaneous adenoid cystic carcinoma. |
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We herein present a case of primary cutaneous cribriform apocrine carcinoma at the neck of a 26-year-old female. The tumor features a relatively well-circumscribed border and multiple aggregations of mildly pleomorphic epithelial cells with large ovoid nuclei, small nucleoli and abundant eosinophilic cytoplasms. Cribriform and tubular structures are the major architectural patterns. The primary differential diagnosis is cutaneous metastasis from a cribriform visceral carcinoma; others include primary secretory carcinoma of the skin, adenoid cystic basal cell carcinoma and primary cutaneous adenoid cystic carcinoma.</description><identifier>ISSN: 0378-6323</identifier><identifier>EISSN: 0973-3922</identifier><identifier>EISSN: 1998-3611</identifier><identifier>DOI: 10.4103/ijdvl.IJDVL_830_16</identifier><identifier>PMID: 29735815</identifier><language>eng</language><publisher>India: Wolters Kluwer India Pvt. 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subjects | Adenocarcinoma - complications Adenocarcinoma - diagnosis Adult Antigens Apocrine Glands - pathology Case reports Case studies Cytoplasm Diagnosis Diagnosis, Differential Female Gangrene Head and neck cancer Human papillomavirus Humans Literature reviews Metastasis Polymerase chain reaction Smooth muscle Stains & staining Sweat Gland Neoplasms - complications Sweat Gland Neoplasms - diagnosis Transcription factors Tumors |
title | Primary cutaneous cribriform apocrine carcinoma: Case report and literature review |
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