Preventing morphine reinforcement with high‐frequency deep brain stimulation of the lateral hypothalamic area

Deep brain stimulation (DBS) has been proposed as a promising intervention for patients with treatment‐refractory substance use disorder. Here, we investigated if high‐frequency DBS in the lateral hypothalamic area (LHA) could affect drug‐induced reinforcement. Rats were bilaterally implanted with b...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Addiction biology 2019-07, Vol.24 (4), p.685-695
Hauptverfasser:	Fattahi, Mojdeh, Ashabi, Ghorbangol, Karimian, Seyed Morteza, Riahi, Esmail
Format:	Artikel
Sprache:	eng
Schlagworte:	Anxiety Clinical trials Deep brain stimulation Drug use Hedonic response Hypothalamus Hypothalamus (lateral) lateral hypothalamic area Morphine Motivation Open-field behavior Place preference conditioning Reinforcement reward substance use disorder Sucrose
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!