Identification of Immune-Responsive Gene 1 (IRG1) as a Target of A20
A20 is a negative regulator of NF-κB signaling; it controls inflammatory responses and ensures tissue homeostasis. A20 is thought to restrict NF-κB activation both by its ubiquitin-editing activity as well as by its nonenzymatic activities. Besides its role in NF-κB signaling, A20 also acts as a pro...
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Veröffentlicht in: | Journal of proteome research 2018-06, Vol.17 (6), p.2182-2191 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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