Identification of Immune-Responsive Gene 1 (IRG1) as a Target of A20

A20 is a negative regulator of NF-κB signaling; it controls inflammatory responses and ensures tissue homeostasis. A20 is thought to restrict NF-κB activation both by its ubiquitin-editing activity as well as by its nonenzymatic activities. Besides its role in NF-κB signaling, A20 also acts as a pro...

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Veröffentlicht in:Journal of proteome research 2018-06, Vol.17 (6), p.2182-2191
Hauptverfasser: Van Quickelberghe, Emmy, Martens, Arne, Goeminne, Ludger J. E, Clement, Lieven, van Loo, Geert, Gevaert, Kris
Format: Artikel
Sprache:eng
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