Parametric study on mixing process in an in-plane spiral micromixer utilizing chaotic advection
Recent advances in the field of microfabrication have made the application of high-throughput microfluidics feasible. Mixing which is an essential part of any miniaturized standalone system remains the key challenge. This paper proposes a geometrically simple micromixer for efficient mixing for high...
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Veröffentlicht in: | Analytica chimica acta 2018-08, Vol.1022, p.96-105 |
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description | Recent advances in the field of microfabrication have made the application of high-throughput microfluidics feasible. Mixing which is an essential part of any miniaturized standalone system remains the key challenge. This paper proposes a geometrically simple micromixer for efficient mixing for high-throughput microfluidic devices. The proposed micromixer utilizes a curved microchannel (spiral microchannel) to induce chaotic advection and enhance the mixing process. It is shown that the spiral microchannel is more efficient in comparison to a straight microchannel, mixing wise. The pressure drop in the spiral microchannel is only slightly higher than that in the straight microchannel. It is found that the mixing process in the spiral microchannel enhances with increasing the inlet velocity, unlike what happens in the straight microchannel. It is also realized that the initial radius of the spiral microchannel plays a prominent role in enhancing the mixing process. Studying different cross sections, it is gathered that the square cross section yields a higher mixing quality.
[Display omitted]
•A high-throughput micromixer is proposed and numerically characterized.•The investigated micromixer has a simple, in-plane structure.•The studied micromixer is energetically efficient; it causes a rather small pressure drop.•Different parameters such as Reynolds number of flow, the curvature and cross-section of the microchannel are investigated.•The dominant mixing mechanism of the spiral micromixer is chaotic advection which makes it high throughput and rapid. |
doi_str_mv | 10.1016/j.aca.2018.03.039 |
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[Display omitted]
•A high-throughput micromixer is proposed and numerically characterized.•The investigated micromixer has a simple, in-plane structure.•The studied micromixer is energetically efficient; it causes a rather small pressure drop.•Different parameters such as Reynolds number of flow, the curvature and cross-section of the microchannel are investigated.•The dominant mixing mechanism of the spiral micromixer is chaotic advection which makes it high throughput and rapid.</description><identifier>ISSN: 0003-2670</identifier><identifier>EISSN: 1873-4324</identifier><identifier>DOI: 10.1016/j.aca.2018.03.039</identifier><identifier>PMID: 29729743</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Advection ; Chaotic advection ; Cross-sections ; Dean flow ; Fluid mechanics ; Microchannels ; Microfluidics ; Mixing quality ; Navier-Stokes equations ; Parametric statistics ; Passive micromixer ; Pressure drop ; Reynolds number ; Semiconductors ; Spiral microchannel ; Vortices</subject><ispartof>Analytica chimica acta, 2018-08, Vol.1022, p.96-105</ispartof><rights>2018 Elsevier B.V.</rights><rights>Copyright © 2018 Elsevier B.V. All rights reserved.</rights><rights>Copyright Elsevier BV Aug 31, 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-9493b076ffed6c8f8f844b6aa0d2ce24504447db2ad587716fc0f1ead69b1c453</citedby><cites>FETCH-LOGICAL-c381t-9493b076ffed6c8f8f844b6aa0d2ce24504447db2ad587716fc0f1ead69b1c453</cites><orcidid>0000-0003-2538-7160</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0003267018304185$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29729743$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vatankhah, Parham</creatorcontrib><creatorcontrib>Shamloo, Amir</creatorcontrib><title>Parametric study on mixing process in an in-plane spiral micromixer utilizing chaotic advection</title><title>Analytica chimica acta</title><addtitle>Anal Chim Acta</addtitle><description>Recent advances in the field of microfabrication have made the application of high-throughput microfluidics feasible. Mixing which is an essential part of any miniaturized standalone system remains the key challenge. This paper proposes a geometrically simple micromixer for efficient mixing for high-throughput microfluidic devices. The proposed micromixer utilizes a curved microchannel (spiral microchannel) to induce chaotic advection and enhance the mixing process. It is shown that the spiral microchannel is more efficient in comparison to a straight microchannel, mixing wise. The pressure drop in the spiral microchannel is only slightly higher than that in the straight microchannel. It is found that the mixing process in the spiral microchannel enhances with increasing the inlet velocity, unlike what happens in the straight microchannel. It is also realized that the initial radius of the spiral microchannel plays a prominent role in enhancing the mixing process. Studying different cross sections, it is gathered that the square cross section yields a higher mixing quality.
[Display omitted]
•A high-throughput micromixer is proposed and numerically characterized.•The investigated micromixer has a simple, in-plane structure.•The studied micromixer is energetically efficient; it causes a rather small pressure drop.•Different parameters such as Reynolds number of flow, the curvature and cross-section of the microchannel are investigated.•The dominant mixing mechanism of the spiral micromixer is chaotic advection which makes it high throughput and rapid.</description><subject>Advection</subject><subject>Chaotic advection</subject><subject>Cross-sections</subject><subject>Dean flow</subject><subject>Fluid mechanics</subject><subject>Microchannels</subject><subject>Microfluidics</subject><subject>Mixing quality</subject><subject>Navier-Stokes equations</subject><subject>Parametric statistics</subject><subject>Passive micromixer</subject><subject>Pressure drop</subject><subject>Reynolds number</subject><subject>Semiconductors</subject><subject>Spiral microchannel</subject><subject>Vortices</subject><issn>0003-2670</issn><issn>1873-4324</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kE1rGzEQhkVJqB23P6CXsJBLL-uMPrzaJadg2qYQSA7pWWil2VZmPxxpN8T59RljJ4ceggYJwTOvRg9j3zgsOfDicrO0zi4F8HIJkqr6xOa81DJXUqgTNgcAmYtCw4ydpbShq-CgPrOZqDSVknNm7m20HY4xuCyNk99lQ5914Tn0f7NtHBymlIU-sz3t-ba1PWZpG6JtCXJxIBJjNo2hDS_7FvfPDiNFWf-EbgxD_4WdNrZN-PV4Ltifnz8e1jf57d2v3-vr29zJko95pSpZgy6aBn3hyoaWUnVhLXjhUKgVKKW0r4X1q1JrXjQOGo7WF1XNnVrJBft-yKWhHydMo-lCctjuJx6mZATIlQYNnBN68R-6GabY03REFRU9BeRwwfiBol-mFLEx2xg6G3eGg9nbNxtD9s3evgFJVVHP-TF5qjv07x1vugm4OgBIKp4CRpNcwN6hD5F8GT-ED-JfAQWMlWs</recordid><startdate>20180831</startdate><enddate>20180831</enddate><creator>Vatankhah, Parham</creator><creator>Shamloo, Amir</creator><general>Elsevier B.V</general><general>Elsevier BV</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QP</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7T7</scope><scope>7TA</scope><scope>7TB</scope><scope>7TK</scope><scope>7TM</scope><scope>7U5</scope><scope>7U7</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2538-7160</orcidid></search><sort><creationdate>20180831</creationdate><title>Parametric study on mixing process in an in-plane spiral micromixer utilizing chaotic advection</title><author>Vatankhah, Parham ; Shamloo, Amir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-9493b076ffed6c8f8f844b6aa0d2ce24504447db2ad587716fc0f1ead69b1c453</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Advection</topic><topic>Chaotic advection</topic><topic>Cross-sections</topic><topic>Dean flow</topic><topic>Fluid mechanics</topic><topic>Microchannels</topic><topic>Microfluidics</topic><topic>Mixing quality</topic><topic>Navier-Stokes equations</topic><topic>Parametric statistics</topic><topic>Passive micromixer</topic><topic>Pressure drop</topic><topic>Reynolds number</topic><topic>Semiconductors</topic><topic>Spiral microchannel</topic><topic>Vortices</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vatankhah, Parham</creatorcontrib><creatorcontrib>Shamloo, Amir</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Toxicology Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Analytica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vatankhah, Parham</au><au>Shamloo, Amir</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Parametric study on mixing process in an in-plane spiral micromixer utilizing chaotic advection</atitle><jtitle>Analytica chimica acta</jtitle><addtitle>Anal Chim Acta</addtitle><date>2018-08-31</date><risdate>2018</risdate><volume>1022</volume><spage>96</spage><epage>105</epage><pages>96-105</pages><issn>0003-2670</issn><eissn>1873-4324</eissn><abstract>Recent advances in the field of microfabrication have made the application of high-throughput microfluidics feasible. Mixing which is an essential part of any miniaturized standalone system remains the key challenge. This paper proposes a geometrically simple micromixer for efficient mixing for high-throughput microfluidic devices. The proposed micromixer utilizes a curved microchannel (spiral microchannel) to induce chaotic advection and enhance the mixing process. It is shown that the spiral microchannel is more efficient in comparison to a straight microchannel, mixing wise. The pressure drop in the spiral microchannel is only slightly higher than that in the straight microchannel. It is found that the mixing process in the spiral microchannel enhances with increasing the inlet velocity, unlike what happens in the straight microchannel. It is also realized that the initial radius of the spiral microchannel plays a prominent role in enhancing the mixing process. Studying different cross sections, it is gathered that the square cross section yields a higher mixing quality.
[Display omitted]
•A high-throughput micromixer is proposed and numerically characterized.•The investigated micromixer has a simple, in-plane structure.•The studied micromixer is energetically efficient; it causes a rather small pressure drop.•Different parameters such as Reynolds number of flow, the curvature and cross-section of the microchannel are investigated.•The dominant mixing mechanism of the spiral micromixer is chaotic advection which makes it high throughput and rapid.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>29729743</pmid><doi>10.1016/j.aca.2018.03.039</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0003-2538-7160</orcidid></addata></record> |
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subjects | Advection Chaotic advection Cross-sections Dean flow Fluid mechanics Microchannels Microfluidics Mixing quality Navier-Stokes equations Parametric statistics Passive micromixer Pressure drop Reynolds number Semiconductors Spiral microchannel Vortices |
title | Parametric study on mixing process in an in-plane spiral micromixer utilizing chaotic advection |
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