Adoptive T cell therapy: points to consider

•Adoptive cellular therapy is represented by 3 major modalities: tumor-infiltrating lymphocyte therapy, CAR/TCR-engineered cell therapy and endogenous T cell therapy.•CAR T cell therapy directed to CD19 demonstrated remarkable efficacy and long-lasting benefit for patients with B cell malignancies.•...

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Veröffentlicht in:	Current opinion in immunology 2018-04, Vol.51, p.197-203
1. Verfasser:	Yee, Cassian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Neoplasm - immunology Genetic Engineering Humans Immunotherapy, Adoptive Lymphocytes, Tumor-Infiltrating - immunology Lymphocytes, Tumor-Infiltrating - metabolism Neoplasms - immunology Neoplasms - metabolism Neoplasms - therapy Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - metabolism Receptors, Chimeric Antigen - genetics Receptors, Chimeric Antigen - metabolism T-Lymphocytes - immunology T-Lymphocytes - metabolism
Online-Zugang:	Volltext
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