Aryl sulfonate based anticancer alkylating agents

This research work revolves around synthesis of antineoplastic alkylating sulfonate esters with dual alkylating sites for crosslinking of the DNA strands. These molecules were evaluated as potential antineoplastic cross linking alkylating agents by reaction with the nucleoside of Guanine DNA nucleob...

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2018-05, Vol.31 (3(Supplementary)), p.1081-1085
Hauptverfasser:	Sheikh, Hamdullah Khadim, Arshad, Tanzila, Kanwal, Ghazala
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylation Analysis Antineoplastic agents Antineoplastic Agents, Alkylating - chemical synthesis Arylsulfonates - chemical synthesis Arylsulfonates - chemistry Busulfan Busulfan - chemistry Cross-Linking Reagents - chemical synthesis Cross-Linking Reagents - chemistry Deoxyguanosine - chemistry Health aspects Properties
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