Effect of Hyperin and Icariin on steroid hormone secretion in rat ovarian granulosa cells

This study was designed to investigate the effect of different concentrations of Hyperin and Icariin (ICA)on proliferation and the secretion of estrogen (E2), and progesterone (P) in granulosa cells, and to explore the effect of Hyperin and Icariin on the expression of CYP17 and CYP19. Rat ovary gra...

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Veröffentlicht in:	Clinica chimica acta 2019-08, Vol.495, p.646-651
Hauptverfasser:	Nie, Xiaowei, Sheng, Wenjie, Hou, Daorong, Liu, Qiang, Wang, Ronggen, Tan, Yong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aromatase - metabolism Cell Proliferation - drug effects CYP17 CYP19 Female Flavonoids - pharmacology Gene Expression Regulation, Enzymologic - drug effects Granulosa Cells - cytology Granulosa Cells - drug effects Granulosa Cells - metabolism Hormones - metabolism Hyperin Icariin Ovarian granulosa cells Quercetin - analogs & derivatives Quercetin - pharmacology Rats Steroid 17-alpha-Hydroxylase - metabolism Steroids - metabolism
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