The Lysosome, Elixir of Neural Stem Cell Youth

The Lysosome, Elixir of Neural Stem Cell Youth

Recently in Science, Leeman et al. find that perturbing lysosomal activity of quiescent NSCs directly impedes their ability to become activated, similar to what happens during aging. Excitingly, they could rejuvenate old quiescent NSCs by enhancing the lysosome pathway, ameliorating their ability to...

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Veröffentlicht in:Cell stem cell 2018-05, Vol.22 (5), p.619-620
Hauptverfasser: Simic, Milos S., Dillin, Andrew
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Cell Division
Lysosomes
Neural Stem Cells
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Dillin, Andrew
description Recently in Science, Leeman et al. find that perturbing lysosomal activity of quiescent NSCs directly impedes their ability to become activated, similar to what happens during aging. Excitingly, they could rejuvenate old quiescent NSCs by enhancing the lysosome pathway, ameliorating their ability to clear protein aggregates and become activated. Recently in Science, Leeman et al. find that perturbing lysosomal activity of quiescent NSCs directly impedes their ability to become activated, similar to what happens during aging. Excitingly, they could rejuvenate old quiescent NSCs by enhancing the lysosome pathway, ameliorating their ability to clear protein aggregates and become activated.
doi_str_mv 10.1016/j.stem.2018.04.017
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subjects Cell Division
Lysosomes
Neural Stem Cells
title The Lysosome, Elixir of Neural Stem Cell Youth
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