Tibolone improves depression in women through the menopause transition: A double-blind randomized controlled trial of adjunctive tibolone

•Depressive symptoms are commonly reported during the menopause transition.•The efficacy of hormone therapy in improving depression experienced during menopause is unclear.•We conducted a randomized control trial to investigate the clinical efficacy of adjunctive tibolone for depression during the m...

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Veröffentlicht in:	Journal of affective disorders 2018-08, Vol.236, p.88-92
Hauptverfasser:	Kulkarni, Jayashri, Gavrilidis, Emorfia, Thomas, Natalie, Hudaib, Abdul-Rahman, Worsley, Roisin, Thew, Caroline, Bleeker, Caitlin, Gurvich, Caroline
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Affect - physiology Antidepressive Agents - therapeutic use Depression - drug therapy Double-Blind Method Estrogen Receptor Modulators - therapeutic use Female Humans Menopause - drug effects Menopause - psychology Middle Aged Norpregnenes - therapeutic use Treatment Outcome
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