IL1β and TNFα promote RANKL-dependent adseverin expression and osteoclastogenesis

Adseverin is an actin-binding protein involved in osteoclastogenesis, but its role in inflammation-induced bone loss is not well-defined. Here, we examined whether IL1β and TNFα regulate adseverin expression to control osteoclastogenesis in mouse primary monocytes and RAW264.7 cells. Adseverin was c...

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Veröffentlicht in:Journal of cell science 2018-06, Vol.131 (11), p.jcs213967-jcs213967
Hauptverfasser: Wang, Yongqiang, Galli, Matthew, Shade Silver, Alexandra, Lee, Wilson, Song, Yushan, Mei, Yixue, Bachus, Carly, Glogauer, Michael, McCulloch, Christopher A
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Sprache:eng
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