Posttranslational Regulation of I-E super(d) by Affinity for CLIP

Several MHC class II alleles linked with autoimmune diseases form unusually low stability complexes with CLIP, leading us to hypothesize that this is an important feature contributing to autoimmune pathogenesis. To investigate cellular consequences of altering class II/CLIP affinity, we evaluated in...

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Veröffentlicht in:The Journal of immunology (1950) 2007-11, Vol.179 (9), p.5907-5915
Hauptverfasser: Rinderknecht, Cornelia H, Belmares, Michael P, Catanzarite, Tatiana LW, Bankovich, Alexander J, Holmes, Tyson H, Garcia, KChristopher, Nanda, Navreet K, Busch, Robert, Kovats, Susan, Mellins, Elizabeth D
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Sprache:eng
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