The emerging role of aldosterone/mineralocorticoid receptors in the pathogenesis of erectile dysfunction

Purpose Aldosterone is an old hormone that has been discovered for more than fifty years. The clinical application of its receptors' inhibitors, especially spirolactone, has benifited patients for decades worldwide. In this review, we briefly summarized the molecular mechanism of aldosterone/mi...

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Veröffentlicht in:	Endocrine 2018-09, Vol.61 (3), p.372-382
Hauptverfasser:	Wu, Fei, Lin, Yun, Liu, Qingyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone Cardiovascular diseases Cardiovascular Diseases - metabolism Diabetes Endocrinology Endothelial cells Endothelial Cells - metabolism Erectile dysfunction Erectile Dysfunction - etiology Erectile Dysfunction - metabolism Humanities and Social Sciences Humans Internal Medicine Male Medicine Medicine & Public Health Mineralocorticoid receptors multidisciplinary Muscle, Smooth, Vascular - metabolism Nitric oxide Nitric-oxide synthase Pathogenesis Reactive oxygen species Reactive Oxygen Species - metabolism Receptors, Mineralocorticoid - metabolism Review Science Smooth muscle
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