Influence of ex vivo perfusion on the biomolecular profile of rat lungs

ABSTRACT Despite increasing clinical adoption, biologic influences of ex vivo lung perfusion (EVLP) remain insufficiently elucidated. The aim of the current study was to investigate biomolecular changes induced by EVLP in rat lungs. EVLP was maintained for 180 min. Hyaluronan, mediators, and cells w...

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Veröffentlicht in:	The FASEB journal 2018-10, Vol.32 (10), p.5532-5549
Hauptverfasser:	Lonati, Caterina, Bassani, Giulia A., Brambilla, Daniela, Leonardi, Patrizia, Carlin, Andrea, Faversani, Alice, Gatti, Stefano, Valenza, Franco
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cell Survival DCD Extracellular Signal-Regulated MAP Kinases - metabolism Heat-Shock Response hyaluronan Hyaluronan Synthases - metabolism Hyaluronic Acid - metabolism ischemic preconditioning Lung - metabolism lung gene expression Male MAP Kinase Signaling System Oxidative Stress Perfusion rat model Rats Rats, Sprague-Dawley
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