Lycopene loaded whey protein isolate nanoparticles: An innovative endeavor for enhanced bioavailability of lycopene and anti-cancer activity

[Display omitted] The work entails a novel strategy of formulating the lycopene loaded whey protein isolate nanoparticles (LYC-WPI-NPs) solely using the rational blend of biomacromolecule without using equipment-intensive techniques. The LYC-WPI-NPs were fabricated as a substantial drug delivery pla...

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Veröffentlicht in:	International journal of pharmaceutics 2018-07, Vol.546 (1-2), p.97-105
Hauptverfasser:	Jain, Ashay, Sharma, Gajanand, Ghoshal, Gargi, Kesharwani, Prashant, Singh, Bhupinder, Shivhare, U.S., Katare, O.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacokinetics Bioavailability Biological Availability Cancer Carotenoids - administration & dosage Carotenoids - chemistry Carotenoids - pharmacokinetics Cell Survival - drug effects Cytotoxicity Drug Carriers - administration & dosage Drug Carriers - chemistry Drug Carriers - pharmacokinetics Drug Liberation Female Gastric Juice - chemistry Humans Intestinal Secretions - chemistry Lycopene Mammary Neoplasms, Experimental - drug therapy MCF-7 Cells Nanoparticles - administration & dosage Nanoparticles - chemistry Rats, Wistar Whey protein isolate Whey Proteins - administration & dosage Whey Proteins - chemistry Whey Proteins - pharmacokinetics
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