C/EBPβ serine 64, a phosphoacceptor site, has a critical role in LPS-induced IL-6 and MCP-1 transcription

C/EBPβ is a member of the CCAAT/enhancer binding protein family of transcription factors and has been shown to be a critical transcriptional regulator of various proinflammatory genes, including IL-6 and MCP-1. Serine 64 in the transactivation domain of C/EBPβ has recently been identified as a Ras-i...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2007-02, Vol.37 (2), p.119-127
Hauptverfasser:	Spooner, Chauncey J., Sebastian, Thomas, Shuman, Jon D., Durairaj, Srinivasan, Guo, Xiangrong, Johnson, Peter F., Schwartz, Richard C.
Format:	Artikel
Sprache:	eng
Schlagworte:	C/EBPβ Gene regulation IL-6 Lipopolysaccharide MCP-1
Online-Zugang:	Volltext
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