Developmental Exposure to Noninherited Maternal Antigens Induces CD4 super(+) T Regulatory Cells: Relevance to Mechanism of Heart Allograft Tolerance

We hypothesize that developmental exposure to noninherited maternal Ags (NIMA) results in alloantigen-specific natural and adaptive T regulatory (T sub(R)) cells. We compared offspring exposed to maternal H-2 super(d) (NIMA super(d)) with nonexposed controls. In vitro assays did not reveal any diffe...

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Veröffentlicht in:	The Journal of immunology (1950) 2007-11, Vol.179 (10), p.6749-6761
Hauptverfasser:	Molitor-Dart, Melanie L, Andrassy, Joachim, Kwun, Jean, Kayaoglu, HAyhan, Roenneburg, Drew A, Haynes, Lynn D, Torrealba, Jose R, Bobadilla, Joseph L, Sollinger, Hans W, Knechtle, Stuart J, Burlingham, William J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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