Time to repeal and replace response criteria for acute myeloid leukemia?

The International Working Group (IWG) response criteria for acute myeloid leukemia, published in 2003, have remained the standard by which the efficacy of new drugs is measured in clinical trials. Over the last decade, concepts related to treatment response have been challenged by several factors; f...

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Veröffentlicht in:	Blood reviews 2018-09, Vol.32 (5), p.416-425
Hauptverfasser:	Bloomfield, Clara Derber, Estey, Elihu, Pleyer, Lisa, Schuh, Andre C., Stein, Eytan M., Tallman, Martin S., Wei, Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia AML Biomarkers, Tumor Clinical trials Combined Modality Therapy Humans Leukemia, Myeloid, Acute - diagnosis Leukemia, Myeloid, Acute - mortality Leukemia, Myeloid, Acute - therapy Minimal residual disease MRD Neoplasm, Residual - diagnosis Prognosis Remission Induction Response criteria Treatment Outcome
Online-Zugang:	Volltext
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