Effects of crude ethanolic extract of Garcinia cambogia on the reproductive system of male wistar rats (Rattus novergicus)
15 male rats were grouped and administered crude ethanolic extracts of Garcinia cambogia seeds to test the effects on the histology of the testis and sperm counts. Group A served as the control while Groups B and C received 100 and 200 mg/kg body weight of extracts, respectively. The administration...
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Veröffentlicht in: | African journal of biotechnology 2007-05, Vol.6 (10), p.1236-1238 |
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creator | Kayode A, O Olusegun R, J Olamide A, A Idowu O, O Sunday J, J Tolulope O, O |
description | 15 male rats were grouped and administered crude ethanolic extracts of Garcinia cambogia seeds to test the effects on the histology of the testis and sperm counts. Group A served as the control while Groups B and C received 100 and 200 mg/kg body weight of extracts, respectively. The administration was done orally once a day, six days a week for six weeks. The routine histological preparation at the end of administration revealed increase in the interstitial spaces, degeneration of the Ledgid cells and distortion in the arrangement of the cells of spermatogenic series. The sperm counts revealed a significant increase in the experimental groups when compared statistically with the control (p |
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Group A served as the control while Groups B and C received 100 and 200 mg/kg body weight of extracts, respectively. The administration was done orally once a day, six days a week for six weeks. The routine histological preparation at the end of administration revealed increase in the interstitial spaces, degeneration of the Ledgid cells and distortion in the arrangement of the cells of spermatogenic series. The sperm counts revealed a significant increase in the experimental groups when compared statistically with the control (p<0.05). It was 81.5 plus or minus 13.62 x 10 super(6)/ml and 70 plus or minus 12.98 x 10 super(6)/ml in groups Band C, respectively, as compared to 59.8 plus or minus 2.14 x 10 super(6)/ml in the Control group.</description><identifier>ISSN: 1684-5315</identifier><identifier>EISSN: 1684-5315</identifier><language>eng</language><subject>Garcinia cambogia ; Rattus</subject><ispartof>African journal of biotechnology, 2007-05, Vol.6 (10), p.1236-1238</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781</link.rule.ids></links><search><creatorcontrib>Kayode A, O</creatorcontrib><creatorcontrib>Olusegun R, J</creatorcontrib><creatorcontrib>Olamide A, A</creatorcontrib><creatorcontrib>Idowu O, O</creatorcontrib><creatorcontrib>Sunday J, J</creatorcontrib><creatorcontrib>Tolulope O, O</creatorcontrib><title>Effects of crude ethanolic extract of Garcinia cambogia on the reproductive system of male wistar rats (Rattus novergicus)</title><title>African journal of biotechnology</title><description>15 male rats were grouped and administered crude ethanolic extracts of Garcinia cambogia seeds to test the effects on the histology of the testis and sperm counts. Group A served as the control while Groups B and C received 100 and 200 mg/kg body weight of extracts, respectively. The administration was done orally once a day, six days a week for six weeks. The routine histological preparation at the end of administration revealed increase in the interstitial spaces, degeneration of the Ledgid cells and distortion in the arrangement of the cells of spermatogenic series. The sperm counts revealed a significant increase in the experimental groups when compared statistically with the control (p<0.05). It was 81.5 plus or minus 13.62 x 10 super(6)/ml and 70 plus or minus 12.98 x 10 super(6)/ml in groups Band C, respectively, as compared to 59.8 plus or minus 2.14 x 10 super(6)/ml in the Control group.</description><subject>Garcinia cambogia</subject><subject>Rattus</subject><issn>1684-5315</issn><issn>1684-5315</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><recordid>eNpNjktLw0AUhYMoWKv_YVaii8Akk8lMllJqFQqC6Lrc3NxpR5JMnUd9_HpTdOHqfHAOH-ckmxW1rnIpCnn6j8-zixDeOC9FWfFZ9r00hjAG5gxDnzpiFHcwut4io8_oAeOxWoFHO1pgCEPrthO4kcUdMU9777qE0R6Iha8QaTjuB-iJfdgQwTMPk_7mGWJMgY3uQH5rMYXby-zMQB_o6i_n2ev98mXxkK-fVo-Lu3W-L3Qdc6F1p7hWEoxUvFYdkW5Fg6VCpYDAiBZblAVRpblsWt2S6RpBAGg4SBLz7PrXOz19TxTiZrABqe9hJJfCpuSiVLUW4ge6PV7I</recordid><startdate>20070516</startdate><enddate>20070516</enddate><creator>Kayode A, O</creator><creator>Olusegun R, J</creator><creator>Olamide A, A</creator><creator>Idowu O, O</creator><creator>Sunday J, J</creator><creator>Tolulope O, O</creator><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20070516</creationdate><title>Effects of crude ethanolic extract of Garcinia cambogia on the reproductive system of male wistar rats (Rattus novergicus)</title><author>Kayode A, O ; Olusegun R, J ; Olamide A, A ; Idowu O, O ; Sunday J, J ; Tolulope O, O</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p186t-388d70875af57067dee8b39c27c77aeaf3bcbc51ee48059b8befd93eaacf0a5e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Garcinia cambogia</topic><topic>Rattus</topic><toplevel>online_resources</toplevel><creatorcontrib>Kayode A, O</creatorcontrib><creatorcontrib>Olusegun R, J</creatorcontrib><creatorcontrib>Olamide A, A</creatorcontrib><creatorcontrib>Idowu O, O</creatorcontrib><creatorcontrib>Sunday J, J</creatorcontrib><creatorcontrib>Tolulope O, O</creatorcontrib><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>African journal of biotechnology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kayode A, O</au><au>Olusegun R, J</au><au>Olamide A, A</au><au>Idowu O, O</au><au>Sunday J, J</au><au>Tolulope O, O</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of crude ethanolic extract of Garcinia cambogia on the reproductive system of male wistar rats (Rattus novergicus)</atitle><jtitle>African journal of biotechnology</jtitle><date>2007-05-16</date><risdate>2007</risdate><volume>6</volume><issue>10</issue><spage>1236</spage><epage>1238</epage><pages>1236-1238</pages><issn>1684-5315</issn><eissn>1684-5315</eissn><abstract>15 male rats were grouped and administered crude ethanolic extracts of Garcinia cambogia seeds to test the effects on the histology of the testis and sperm counts. Group A served as the control while Groups B and C received 100 and 200 mg/kg body weight of extracts, respectively. The administration was done orally once a day, six days a week for six weeks. The routine histological preparation at the end of administration revealed increase in the interstitial spaces, degeneration of the Ledgid cells and distortion in the arrangement of the cells of spermatogenic series. The sperm counts revealed a significant increase in the experimental groups when compared statistically with the control (p<0.05). It was 81.5 plus or minus 13.62 x 10 super(6)/ml and 70 plus or minus 12.98 x 10 super(6)/ml in groups Band C, respectively, as compared to 59.8 plus or minus 2.14 x 10 super(6)/ml in the Control group.</abstract><tpages>3</tpages></addata></record> |
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title | Effects of crude ethanolic extract of Garcinia cambogia on the reproductive system of male wistar rats (Rattus novergicus) |
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