The secretion of human T cell leukemia virus type 1 Tax protein is a regulated process involving components of cellular secretory pathway and critical amino acid signals within the viral protein: Implications for HTLV-1 neuropathogenesis

HTLV-1 associated myelopathy/tropical spastic para-paresis (HAM/TSP) is a progressive neurological disorder. Many pathologic abnormalities associated with HAM/TSP have been attributed to the extracellular activity of the viral transactivator protein Tax. Cell-free Tax has been detected in the cerebr...

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Veröffentlicht in:Journal of neurovirology 2007-01, Vol.13, p.89-89
Hauptverfasser: Jain, P, Mostoller, K, Flaig, KE, Lepoutre, V, Ahuja, J, Wigdahl, B
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Sprache:eng
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