Proteomic analysis of age-related changes in ovine cerebrospinal fluid

Cerebrospinal fluid (CSF) circulates through the brain and has a unique composition reflecting the biological processes of the brain. Identifying ageing CSF biomarkers can aid in understanding the ageing process and interpreting CSF protein changes in neurodegenerative diseases. In this study, ovine...

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Veröffentlicht in:	Experimental gerontology 2018-07, Vol.108, p.181-188
Hauptverfasser:	Chen, Carl P.C., Preston, Jane E., Zhou, Shaobo, Fuller, Heidi R., Morgan, David G.A., Chen, Ruoli
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing Aging - cerebrospinal fluid Animals Biomarkers Biomarkers - cerebrospinal fluid Choroid plexus Chromatography, High Pressure Liquid CSF Female Neurodegenerative disease Neurodegenerative Diseases - cerebrospinal fluid Neurodegenerative Diseases - diagnosis Peptide Fragments - cerebrospinal fluid Proteomics Sheep Tandem Mass Spectrometry
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