Visualization of the activation of the histamine H3 receptor (H3R) using novel fluorescence resonance energy transfer biosensors and their potential application to the study of H3R pharmacology

Activation of the histamine‐3 receptor (H3R) is involved in memory processes and cognitive action, while blocking H3R activation can slow the progression of neurological disorders, such as Alzheimer's disease, schizophrenia and narcolepsy. To date, however, no direct way to examine the activati...

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Veröffentlicht in:The FEBS journal 2018-06, Vol.285 (12), p.2319-2336
Hauptverfasser: Liu, Ying, Zeng, Hong, Pediani, John D., Ward, Richard J., Chen, Lu‐Yao, Wu, Nan, Ma, Li, Tang, Mei, Yang, Yang, An, Su, Guo, Xiao‐Xi, Hao, Qian, Xu, Tian‐Rui
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Sprache:eng
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