Synthesis of (E)-cinnamyl ester derivatives via a greener Steglich esterification

[Display omitted] Cinnamic acid derivatives are known antifungal, antimicrobial, antioxidant, and anticancer compounds. We have developed a facile and mild methodology for the synthesis of (E)-cinnamate derivatives using a modified Steglich esterification of (E)-cinnamic acid. Using acetonitrile as...

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Veröffentlicht in:	Bioorganic & medicinal chemistry 2018-10, Vol.26 (19), p.5291-5298
Hauptverfasser:	Lutjen, Andrew B., Quirk, Mackenzie A., Barbera, Allycia M., Kolonko, Erin M.
Format:	Artikel
Sprache:	eng
Schlagworte:	(E)-Cinnamic acid Acetonitriles - chemistry Cinnamates - chemical synthesis Cinnamates - chemistry Cinnamyl ester derivatives Esterification Esters - chemical synthesis Esters - chemistry Green solvent Propanols - chemistry Steglich esterification Stereoisomerism Temperature
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