Allergic disorders: A model for establishing how to prevent common disease

Allergy to common agents, such as plant pollens, dust mites and foods, is termed atopy. Atopy is the principal cause of the chronic inflammatory diseases of eczema (the skin), hayfever (the nose) and asthma (the lungs) in children and young adults. Atopy affects millions of individuals in Japan and...

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Veröffentlicht in:Allergology international 2004, Vol.53 (2), p.61-68
Hauptverfasser: Yamasaki, Akiko, Cheng, Lei, Fukuda, Sanae, Chinami, Masanobu, Fujita, Daisuke, Wasserman, Danuta, Shirakawa, Taro
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container_end_page 68
container_issue 2
container_start_page 61
container_title Allergology international
container_volume 53
creator Yamasaki, Akiko
Cheng, Lei
Fukuda, Sanae
Chinami, Masanobu
Fujita, Daisuke
Wasserman, Danuta
Shirakawa, Taro
description Allergy to common agents, such as plant pollens, dust mites and foods, is termed atopy. Atopy is the principal cause of the chronic inflammatory diseases of eczema (the skin), hayfever (the nose) and asthma (the lungs) in children and young adults. Atopy affects millions of individuals in Japan and other developed countries and is a major source of chronic ill health in childhood and of major health expenditure. Current treatments only control symptoms and there is an urgent need for a more fundamental understanding of the origins of atopy in order to plan more effective treatment and prevention. This may become a useful model for other common multifactorial disease.
doi_str_mv 10.1111/j.1440-1592.2004.00333.x
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subjects allergy
Dermatophagoides
hygiene hypothesis
IgE
interleukin‐13
interleukin‐4
single nucleotide polymorphisms
title Allergic disorders: A model for establishing how to prevent common disease
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