Comparison of changes of macular ganglion cell-inner plexiform layer defect between stable group and progression group in primary open-angle glaucoma
Purpose To compare the changes in macular ganglion cell-inner plexiform layer (GCIPL) defect between stable and progression primary open-angle glaucoma (POAG) groups. Study design Retrospective observational study. Methods A total of 100 POAG eyes with localized retinal nerve fiber layer (RNFL) defe...
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| Veröffentlicht in: | Japanese journal of ophthalmology 2018-07, Vol.62 (4), p.491-498 |
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| creator | Seol, Bo Ram Yoo, Byeong Wook Kim, Young Kook Jeoung, Jin Wook Park, Ki Ho |
| description | Purpose
To compare the changes in macular ganglion cell-inner plexiform layer (GCIPL) defect between stable and progression primary open-angle glaucoma (POAG) groups.
Study design
Retrospective observational study.
Methods
A total of 100 POAG eyes with localized retinal nerve fiber layer (RNFL) defect and corresponding macular GCIPL defect were selected for this study. Glaucoma progression was defined by either structural or functional deterioration. The number of abnormal superpixels on macular GCIPL deviation maps was calculated using a customized MATLAB program. GCIPL defect change was evaluated in two aspects: increased angular width and increased area. The defect patterns were categorized and compared between the stable and progression groups.
Results
The increase rate of angular width of GCIPL defect was higher in the progression group than in the stable group (P = 0.029). In respect to the area of GCIPL defect, there was no statistically significant differences between the groups (P = 0.227). Twenty-seven (27) of 100 (27.0%) eyes showed increased angular width of GCIPL defect. It was more frequent in the progression group than in the stable group (P = 0.043). Seventeen (17) of 27 (63.0%) eyes showed the away from the horizontal temporal raphe type progression and it was the most common change pattern of angular width of GCIPL defect.
Conclusions
Increased angular width of GCIPL defect was the more prominent feature of change, and was more frequent in the progression group than in the stable group. Among the types of GCIPL defect classified, the away from the horizontal temporal raphe type was the most common. |
| doi_str_mv | 10.1007/s10384-018-0593-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2031420792</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2031420792</sourcerecordid><originalsourceid>FETCH-LOGICAL-c396t-783c63385e8334968304c5d08ceb95042c750376ffe04b2764853fc0fd4b9e43</originalsourceid><addsrcrecordid>eNp1kctu1TAQhi1ERQ9tH4ANssSGjen4mmSJjspFqsSme8txJodUiR3sRNAH4X1xlANISKxsz3zzz4x_Ql5xeMcBqtvMQdaKAa8Z6EYy84wcuOGSCaHMc3IAEJxprvUleZnzIwAoIcULcika0xhl1IH8PMZpdmnIMdDYU__VhRPm7To5v44u0VOJjENJexxHNoSAic4j_hj6mCY6uqfy7rBHv9AWl--IgebFtSPSU4rrTF3o6JziKWHOm8weHUIJDpNLTzTOGNjWpFSMbvVxctfkondjxpvzeUUePtw9HD-x-y8fPx_f3zMvG7OwqpbeSFlrrKVUjaklKK87qD22jS7L-kqDrEzfI6hWVEbVWvYe-k61DSp5Rd7usmW-byvmxU5D3tZ0AeOarQDJlYCqEQV98w_6GNcUynAbBVqVL4VC8Z3yKeacsLfnJS0Hu1lmd8tsscxulllTal6fldd2wu5PxW-PCiB2IJdUcSf9bf1_1V_EEaLJ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2030542960</pqid></control><display><type>article</type><title>Comparison of changes of macular ganglion cell-inner plexiform layer defect between stable group and progression group in primary open-angle glaucoma</title><source>SpringerLink Journals - AutoHoldings</source><creator>Seol, Bo Ram ; Yoo, Byeong Wook ; Kim, Young Kook ; Jeoung, Jin Wook ; Park, Ki Ho</creator><creatorcontrib>Seol, Bo Ram ; Yoo, Byeong Wook ; Kim, Young Kook ; Jeoung, Jin Wook ; Park, Ki Ho</creatorcontrib><description>Purpose
To compare the changes in macular ganglion cell-inner plexiform layer (GCIPL) defect between stable and progression primary open-angle glaucoma (POAG) groups.
Study design
Retrospective observational study.
Methods
A total of 100 POAG eyes with localized retinal nerve fiber layer (RNFL) defect and corresponding macular GCIPL defect were selected for this study. Glaucoma progression was defined by either structural or functional deterioration. The number of abnormal superpixels on macular GCIPL deviation maps was calculated using a customized MATLAB program. GCIPL defect change was evaluated in two aspects: increased angular width and increased area. The defect patterns were categorized and compared between the stable and progression groups.
Results
The increase rate of angular width of GCIPL defect was higher in the progression group than in the stable group (P = 0.029). In respect to the area of GCIPL defect, there was no statistically significant differences between the groups (P = 0.227). Twenty-seven (27) of 100 (27.0%) eyes showed increased angular width of GCIPL defect. It was more frequent in the progression group than in the stable group (P = 0.043). Seventeen (17) of 27 (63.0%) eyes showed the away from the horizontal temporal raphe type progression and it was the most common change pattern of angular width of GCIPL defect.
Conclusions
Increased angular width of GCIPL defect was the more prominent feature of change, and was more frequent in the progression group than in the stable group. Among the types of GCIPL defect classified, the away from the horizontal temporal raphe type was the most common.</description><identifier>ISSN: 0021-5155</identifier><identifier>EISSN: 1613-2246</identifier><identifier>DOI: 10.1007/s10384-018-0593-6</identifier><identifier>PMID: 29696464</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Clinical Investigation ; Defects ; Design defects ; Eye ; Eye (anatomy) ; Glaucoma ; Horizontal cells ; Medicine ; Medicine & Public Health ; Ophthalmology ; Retina ; Statistical analysis ; Structure-function relationships</subject><ispartof>Japanese journal of ophthalmology, 2018-07, Vol.62 (4), p.491-498</ispartof><rights>Japanese Ophthalmological Society 2018</rights><rights>Japanese Journal of Ophthalmology is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-783c63385e8334968304c5d08ceb95042c750376ffe04b2764853fc0fd4b9e43</citedby><cites>FETCH-LOGICAL-c396t-783c63385e8334968304c5d08ceb95042c750376ffe04b2764853fc0fd4b9e43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10384-018-0593-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10384-018-0593-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27922,27923,41486,42555,51317</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29696464$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Seol, Bo Ram</creatorcontrib><creatorcontrib>Yoo, Byeong Wook</creatorcontrib><creatorcontrib>Kim, Young Kook</creatorcontrib><creatorcontrib>Jeoung, Jin Wook</creatorcontrib><creatorcontrib>Park, Ki Ho</creatorcontrib><title>Comparison of changes of macular ganglion cell-inner plexiform layer defect between stable group and progression group in primary open-angle glaucoma</title><title>Japanese journal of ophthalmology</title><addtitle>Jpn J Ophthalmol</addtitle><addtitle>Jpn J Ophthalmol</addtitle><description>Purpose
To compare the changes in macular ganglion cell-inner plexiform layer (GCIPL) defect between stable and progression primary open-angle glaucoma (POAG) groups.
Study design
Retrospective observational study.
Methods
A total of 100 POAG eyes with localized retinal nerve fiber layer (RNFL) defect and corresponding macular GCIPL defect were selected for this study. Glaucoma progression was defined by either structural or functional deterioration. The number of abnormal superpixels on macular GCIPL deviation maps was calculated using a customized MATLAB program. GCIPL defect change was evaluated in two aspects: increased angular width and increased area. The defect patterns were categorized and compared between the stable and progression groups.
Results
The increase rate of angular width of GCIPL defect was higher in the progression group than in the stable group (P = 0.029). In respect to the area of GCIPL defect, there was no statistically significant differences between the groups (P = 0.227). Twenty-seven (27) of 100 (27.0%) eyes showed increased angular width of GCIPL defect. It was more frequent in the progression group than in the stable group (P = 0.043). Seventeen (17) of 27 (63.0%) eyes showed the away from the horizontal temporal raphe type progression and it was the most common change pattern of angular width of GCIPL defect.
Conclusions
Increased angular width of GCIPL defect was the more prominent feature of change, and was more frequent in the progression group than in the stable group. Among the types of GCIPL defect classified, the away from the horizontal temporal raphe type was the most common.</description><subject>Clinical Investigation</subject><subject>Defects</subject><subject>Design defects</subject><subject>Eye</subject><subject>Eye (anatomy)</subject><subject>Glaucoma</subject><subject>Horizontal cells</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Ophthalmology</subject><subject>Retina</subject><subject>Statistical analysis</subject><subject>Structure-function relationships</subject><issn>0021-5155</issn><issn>1613-2246</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kctu1TAQhi1ERQ9tH4ANssSGjen4mmSJjspFqsSme8txJodUiR3sRNAH4X1xlANISKxsz3zzz4x_Ql5xeMcBqtvMQdaKAa8Z6EYy84wcuOGSCaHMc3IAEJxprvUleZnzIwAoIcULcika0xhl1IH8PMZpdmnIMdDYU__VhRPm7To5v44u0VOJjENJexxHNoSAic4j_hj6mCY6uqfy7rBHv9AWl--IgebFtSPSU4rrTF3o6JziKWHOm8weHUIJDpNLTzTOGNjWpFSMbvVxctfkondjxpvzeUUePtw9HD-x-y8fPx_f3zMvG7OwqpbeSFlrrKVUjaklKK87qD22jS7L-kqDrEzfI6hWVEbVWvYe-k61DSp5Rd7usmW-byvmxU5D3tZ0AeOarQDJlYCqEQV98w_6GNcUynAbBVqVL4VC8Z3yKeacsLfnJS0Hu1lmd8tsscxulllTal6fldd2wu5PxW-PCiB2IJdUcSf9bf1_1V_EEaLJ</recordid><startdate>20180701</startdate><enddate>20180701</enddate><creator>Seol, Bo Ram</creator><creator>Yoo, Byeong Wook</creator><creator>Kim, Young Kook</creator><creator>Jeoung, Jin Wook</creator><creator>Park, Ki Ho</creator><general>Springer Japan</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20180701</creationdate><title>Comparison of changes of macular ganglion cell-inner plexiform layer defect between stable group and progression group in primary open-angle glaucoma</title><author>Seol, Bo Ram ; Yoo, Byeong Wook ; Kim, Young Kook ; Jeoung, Jin Wook ; Park, Ki Ho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-783c63385e8334968304c5d08ceb95042c750376ffe04b2764853fc0fd4b9e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Clinical Investigation</topic><topic>Defects</topic><topic>Design defects</topic><topic>Eye</topic><topic>Eye (anatomy)</topic><topic>Glaucoma</topic><topic>Horizontal cells</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Ophthalmology</topic><topic>Retina</topic><topic>Statistical analysis</topic><topic>Structure-function relationships</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Seol, Bo Ram</creatorcontrib><creatorcontrib>Yoo, Byeong Wook</creatorcontrib><creatorcontrib>Kim, Young Kook</creatorcontrib><creatorcontrib>Jeoung, Jin Wook</creatorcontrib><creatorcontrib>Park, Ki Ho</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Japanese journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Seol, Bo Ram</au><au>Yoo, Byeong Wook</au><au>Kim, Young Kook</au><au>Jeoung, Jin Wook</au><au>Park, Ki Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of changes of macular ganglion cell-inner plexiform layer defect between stable group and progression group in primary open-angle glaucoma</atitle><jtitle>Japanese journal of ophthalmology</jtitle><stitle>Jpn J Ophthalmol</stitle><addtitle>Jpn J Ophthalmol</addtitle><date>2018-07-01</date><risdate>2018</risdate><volume>62</volume><issue>4</issue><spage>491</spage><epage>498</epage><pages>491-498</pages><issn>0021-5155</issn><eissn>1613-2246</eissn><abstract>Purpose
To compare the changes in macular ganglion cell-inner plexiform layer (GCIPL) defect between stable and progression primary open-angle glaucoma (POAG) groups.
Study design
Retrospective observational study.
Methods
A total of 100 POAG eyes with localized retinal nerve fiber layer (RNFL) defect and corresponding macular GCIPL defect were selected for this study. Glaucoma progression was defined by either structural or functional deterioration. The number of abnormal superpixels on macular GCIPL deviation maps was calculated using a customized MATLAB program. GCIPL defect change was evaluated in two aspects: increased angular width and increased area. The defect patterns were categorized and compared between the stable and progression groups.
Results
The increase rate of angular width of GCIPL defect was higher in the progression group than in the stable group (P = 0.029). In respect to the area of GCIPL defect, there was no statistically significant differences between the groups (P = 0.227). Twenty-seven (27) of 100 (27.0%) eyes showed increased angular width of GCIPL defect. It was more frequent in the progression group than in the stable group (P = 0.043). Seventeen (17) of 27 (63.0%) eyes showed the away from the horizontal temporal raphe type progression and it was the most common change pattern of angular width of GCIPL defect.
Conclusions
Increased angular width of GCIPL defect was the more prominent feature of change, and was more frequent in the progression group than in the stable group. Among the types of GCIPL defect classified, the away from the horizontal temporal raphe type was the most common.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>29696464</pmid><doi>10.1007/s10384-018-0593-6</doi><tpages>8</tpages></addata></record> |
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| ispartof | Japanese journal of ophthalmology, 2018-07, Vol.62 (4), p.491-498 |
| issn | 0021-5155 1613-2246 |
| language | eng |
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| source | SpringerLink Journals - AutoHoldings |
| subjects | Clinical Investigation Defects Design defects Eye Eye (anatomy) Glaucoma Horizontal cells Medicine Medicine & Public Health Ophthalmology Retina Statistical analysis Structure-function relationships |
| title | Comparison of changes of macular ganglion cell-inner plexiform layer defect between stable group and progression group in primary open-angle glaucoma |
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