Brain white matter microstructural alterations in children of type I Gaucher disease characterized with diffusion tensor MR imaging

•WM microstructural alterations were found in children with type I GD.•The disease duration was significantly correlated with the WM microstructural changes.•DTI can be used to evaluate brain microstructural alterations in GD.•Neurological and cognitive symptoms should be monitored in GD during the...

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Veröffentlicht in:European journal of radiology 2018-05, Vol.102, p.22-29
Hauptverfasser: Kang, Huiying, Zhang, Miao, Ouyang, Minhui, Guo, Ruolan, Yu, Qinlin, Peng, Qinmu, Zhang, Ningning, Zhang, Yonghong, Duan, Yanlong, Tang, Xiaolu, Mishra, Virendra, Fang, Fang, Li, Wei, Huang, Hao, Peng, Yun
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Sprache:eng
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