Effect of Enzymatic Digestion of Protein Derivatives Obtained from Mucuna pruriens L. on Production of Proinflammatory Mediators by BALB/c Mouse Macrophages

Inflammation is considered to be a major risk factor for the pathogenesis of chronic non-communicable diseases. Macrophages are important immune cells, which regulate inflammation and host defense by secretion of proinflammatory mediators. Obtaining biopeptides by enzymatic hydrolysis adds value to...

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Veröffentlicht in:	Applied biochemistry and biotechnology 2018-11, Vol.186 (3), p.597-612
Hauptverfasser:	Martínez Leo, Edwin E., Arana Argáez, Victor E., Acevedo Fernández, Juan J., Puc, Rosa Moo, Segura Campos, Maira R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Biochemistry Biotechnology Cercopithecus aethiops Chemistry Chemistry and Materials Science Derivatives Digestion Enzymes - metabolism Hydrogen peroxide Hydrolysis Immune system Inflammation Inflammation Mediators - metabolism Interleukin 6 Interleukin-6 - biosynthesis Macrophages Macrophages - metabolism Male Mice, Inbred BALB C Molecular Weight Mucuna - chemistry Mucuna pruriens Pathogenesis Peptides - chemistry Peptides - metabolism Plant Proteins - chemistry Plant Proteins - metabolism Proteins Proteolysis Risk factors Rodents Transforming Growth Factor alpha - biosynthesis Tumor necrosis factor-α Vero Cells
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