The functional variant of the inhibitory Fcγ receptor IIb (CD32B) is associated with the rate of radiologic joint damage and dendritic cell function in rheumatoid arthritis

Objective Fcγ receptors (FcγRs) recognize immune complexes (ICs) and coordinate the immune response by modulating the functions of dendritic cells (DCs). The purpose of this study was to unravel the role of the inhibitory FcγRIIb in rheumatoid arthritis (RA) by studying the effect of the FCGR2B 695T...

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Veröffentlicht in:Arthritis and rheumatism 2006-12, Vol.54 (12), p.3828-3837
Hauptverfasser: Radstake, Timothy R. D. J., Franke, Barbara, Wenink, Mark H., Nabbe, Karin C. A. M., Coenen, Marieke J. H., Welsing, Paco, Bonvini, Ezio, Koenig, Scott, Berg, Wim B. van den, Barrera, Pilar, van Riel, Piet L. C. M.
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Sprache:eng
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