A combinatorial modulation of synaptic plasticity in the rat medial amygdala by oxytocin, urocortin3 and estrogen

•We demonstrate a bidirectional long-term plasticity in AOB-MeA synaptic pathway.•This plasticity is modulated in a combinatorial manner by three neuromodulators.•While oxytocin causes LTD, combining it with urocortin3 or estrogen causes LTP.•The effect of urocortin3 is mediated by the CRFR2 recepto...

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Veröffentlicht in:	Psychoneuroendocrinology 2018-06, Vol.92, p.95-102
Hauptverfasser:	Frankiensztajn, Linoy Mia, Gur-Pollack, Rotem, Wagner, Shlomo
Format:	Artikel
Sprache:	eng
Schlagworte:	Estrogen Medial amygdala Oxytocin Social recognition memory Synaptic plasticity Urocortin3
Online-Zugang:	Volltext
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